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Diagnoses

Patients who have been ill for years with Th1/Th17 inflammatory symptoms usually collect a wide range of diagnostic labels in their quest for answers. A diagnosis is just a doctor's best guess, and can at times be useful to help determine treatment choices in some diseases or for getting disability. Some doctors order specialized testing to try to verify all possible diagnoses because they are thinking of them as separate diseases and do not recognize the common etiology. The determination to thoroughly test and diagnose is based on the premise that symptoms can then be managed, or individualized treatment can be determined.
 
However, all the so-called ‘autoimmune’ diseases and many chronic illnesses are now believed to be variations of the Th1/Th17 inflammatory process. An exact diagnosis isn't important.
 
”I have several diagnoses that I believe are all due to Th1/Th17 inflammation. These labels refer to the damage that the inflammation has done to my body but do not explain why. I much prefer the following diagnostic label because it explains the root cause of the clinical picture.
 
”Hypervitaminosis-D (proven by blood work) resulting in symptoms of Th1/Th17 inflammation due to systemic chronic intracellular infection, as evidenced by Herxheimer reaction, and also evidenced by resolution of abnormal blood work and inflammatory symptoms with Inflammation Therapy.
 
"Not very catchy but it points to the correct treatment which will eliminate the cause and thus the disease/s.” Meg Mangin, R.N.
 
Diagnosing Th1/Th17 inflammation
 
Specific diagnostic labels aren't needed to begin Inflammation Therapy (IT). For example, it isn't necessary to undergo invasive and risky tests (e.g., lung biopsy, spinal tap, bone marrow biopsy) or expensive tests to locate inflamed tissues.
 
To verify inflammatory illness and dysregulated vitamin D metabolism, we recommend measuring two D-metabolites:
  • 1,25-dihydroxyvitamin-D (125-D)
  • 25-hydroxyvitamin-D (25D or D2/D3)

Assessing labs is desirable before initiating therapy to establish a baseline before treatment. The following tests are recommended:

  • Complete blood count (CBC)
  • Comprehensive metabolic panel (CMP)
  • TSH
  • Liver enzymes

See also:

 
 
 
 
Identifying pathogens
 
Identification of specific pathogens isn't necessary to begin Inflammation Therapy. Trying to pinpoint a specific organism and testing for antibodies is futile and unnecessary because bacteria living within the monocytes and macrophages can't be detected by routine lab tests.
 
Cell wall deficient (CWD) bacteria only move out of the infected cells when the cells die. They use biochemical mechanisms to delay apoptosis (cell death) and make the cell stay intact as long as possible. When the cells die (apoptosis or phagocytosis) it might be possible to see them at that point with PCR (polymerase chain reaction) testing if the PCR probe sequence is general enough. But PCR testing is expensive and only done in specialty labs.
 
Antibodies found in the blood are due to the pathogens which were unsuccessful, the ones that were killed by the immune system. These are not the pathogens that cause Th1 inflammation. The intracellular bacteria which cause Th1 inflammation do not appear in antibody assays.
 
Biopsy testing doesn't usually look for intracellular bacteria and they would be difficult to identify because the bacteria are destroyed when taken out of the body; their protective homeostasis is lost and the lysosomes in the immune system kill them.